Zambia, who are fielding two teams, must overcome stiff competition from Botswana, Zimbabwe, Lesotho and Democratic Republic of Congo (DRC).
This Pool A encounter will set the tone for Zambia’s path and the Musonda Kaminsa-tutored side will be eager to get a win.
Kaminsa will rely on skipper Israel Kalumba, Kapindu Nyangu Guy Lipschitz, Jeremy Badcock and Lastone Mukosa for victory.
But the Tswanas have come with live ammunition and will not be pushovers.
Zimbabwe Goshawks, DRC and Copperbelt Select are the other teams in the group.
To keep alive the chances of ensuring that the trophy remains in Zambia, the B side under the tutelage of Reuben Mkandawire must be at its best from the start.
In Berthlock Sikaona, Daniel Luyt, Derrick Chewe, Melvin Banda, Brian West and Brian Mbalwa, Mkandwire has match winners.